Houston Astros in Preseason Top 500
Glossary for future grades: h-hit tool, p-power tool, s-speed tool, fb-fastball, sl-slider, cv-curveball, ch-change-up, ct-cutter, fv-future value overall.
| NO. | NAME | POS | B/T | FUTURE GRADES | LEVEL | AGE | ETA |
| 1 | Hunter Brown | SP | R/R | 70fb-60cv-50sl-50ch-55fv | MLB | 24 | now |
| 2 | Yainer Diaz | C | R/R | 60h-50p-35s-50fv | MLB | 24 | early-2023 |
| 3 | Pedro Leon | OF | R/R | 40h-55p-70s-50fv | AAA | 25 | early-2023 |
| 4 | Drew Gilbert | OF | L/L | 55h-45p-55s-50fv | Low-A | 22 | 2025 |
| 5 | Jacob Melton | OF | L/L | 50h-55p-60s-45fv | Low-A | 22 | 2025 |
| 6 | Colin Barber | OF | L/L | 50h-50p-55s-45fv | High-A | 22 | mid-2023 |
| 7 | Korey Lee | C | R/R | 40h-55p-40s-45fv | AAA | 24 | early-2023 |
| 8 | Miguel Ullola | SP | R/R | 65fb-50cv-55sl-45ch-45fv | Low-A | 21 | 2024 |
| 9 | Joe Perez | 3B | R/R | 45h-55p-30s-45fv | AAA | 23 | mid-2023 |
| 10 | Will Wagner | 2B | L/R | 50h-40p-45s-45fv | AA | 24 | late-2023 |
| 11 | Spencer Arrighetti | SP | R/R | 60fb-50cv-55sl-45ch-45fv | High-A | 22 | 2024 |
| 12 | David Hensley | IF | R/R | 55h-50p-50s-45fv | AAA | 26 | early-2023 |
| 13 | Justin Dirden | OF | L/R | 50h-50p-45s-45fv | AAA | 26 | mid-2023 |
| 14 | Kenedy Corona | OF | R/R | 50h-40p-50s-45fv | High-A | 23 | 2024 |
| 15 | Camilo Diaz | OF | R/R | 55h-50p-50s-45fv | n/a | 17 | 2027 |