Chicago White Sox in Preseason Top 500
Glossary for future grades: h-hit tool, p-power tool, s-speed tool, fb-fastball, sl-slider, cv-curveball, ch-change-up, ct-cutter, fv-future value overall.
| NO. | NAME | POS | B/T | FUTURE GRADES | LEVEL | AGE | ETA |
| 1 | Colson Montgomery | SS | L/R | 55h-55p-50s-60fv | AA | 21 | 2024 |
| 2 | Oscar Colas | OF | L/L | 55h-60p-40s-55fv | AAA | 24 | early-2023 |
| 3 | Bryan Ramos | 3B | R/R | 50h-50p-45s-50fv | AA | 21 | mid-2023 |
| 4 | Jose Rodriguez | SS | R/R | 55h-50p-55s-45fv | AA | 22 | late-2023 |
| 5 | Lenyn Sosa | 2B | R/R | 50h-50p-40s-45fv | AAA | 23 | mid-2023 |
| 6 | Cristian Mena | SP | R/R | 50fb-60cv-50ch-45fv | AA | 20 | late-2023 |
| 7 | Norge Vera | SP | R/R | 70fb-55sl-50ch-45fv | AA | 23 | late-2023 |
| 8 | Yoelqui Cespedes | OF | R/R | 45h-50p-55s-45fv | AA | 25 | mid-2023 |
| 9 | Noah Schultz | SP | L/L | 55fb-60sl-50ch-45fv | n/a | 18 | 2026 |
| 10 | Sean Burke | SP | R/R | 55fb-55cv-55sl-45ch-45fv | AA | 23 | late-2023 |
| 11 | Peyton Pallatte | SP | R/R | 60fb-65cv-50ch-45fv | n/a | 21 | 2025 |